READY TO GET STARTED?

First, let’s find a doctor

ZILRETTA is administered in a doctor’s office. This is typically done by a specialist, such as an orthopedic surgeon or a sports medicine physician.

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Getting ready for your appointment

Now that you’ve found a doctor who administers ZILRETTA, let’s prepare for success.

Tips to help you prepare:

Understand your insurance coverage – Talk to your doctor to see if ZILRETTA is covered. If you have Medicare Part B, ZILRETTA is covered. The majority of private health insurance plans also cover ZILRETTA.

Set personal goals – Before seeing a doctor, set short- and long-term goals for managing your osteoarthritis knee pain. These can help you both decide on a treatment approach that could help you reach your goals.

Be specific – When talking about personal goals, symptoms, or your experience with different treatment approaches, try to be as specific as possible.

Ask questions – Get details about the recommended treatment options, how they work, what to expect, what risks you may need to watch out for, and how long you may experience the positive effects of the treatment.

Pay attention for symptoms – Make sure to write down all of your symptoms. And think beyond pain—which activities are harder because of osteoarthritis knee pain?

Download and print out your Symptom Summary, fill it in, and then bring it to your appointment.

Symptom Summary

During your appointment

Don’t leave your appointment unsure about something. Ask questions. Your doctor will be happy you did.

During your ZILRETTA injection appointment

Here's some tips:

Share – Always give specific examples of your condition to your doctor. Make sure to tell them how much it hurts and when.

And don't forget:

Treatments you’ve already had
Medications you’ve tried
Physical therapy and exercises you’ve tried
How well they worked (or didn’t)
How long they lasted

Speak up – Don’t be afraid to share your thoughts and ask about treatment options for osteoarthritis knee pain. If you didn’t understand something, ask your doctor to clarify. If you feel like you need more time, let your doctor know.

Listen with a pen – Take advantage of face-to-face time with your doctor—bring a list of questions to ask and take notes.

Get more insights:

10 Ways to Maximize Time With Your Doctor Doctor Discussion Guide

What to expect afterward

You should be feeling the results of your injection soon, if not already. Enjoy this time, but don’t forget to keep an eye on your knee.

Some things you should know, now that you’ve had the Z:

Call your doctor if you have a reaction at the injection site or experience any side effects
Stay active. You can help control stiffness and pain if you keep your knee in motion
Now that you’ve had your treatment, pay attention to how ZILRETTA works for you

Track your treatment

Help your doctor understand your overall ZILRETTA experience by keeping a log of:

How much pain relief it provided
How long the pain relief lasted

Download and print out these helpful tips:

Post-Injection Tips

Enter your location and see a list of providers who perform ZILRETTA treatments near you.

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Indication and Important Risk Information

What is ZILRETTA?

ZILRETTA^® (triamcinolone acetonide extended-release injectable suspension) is an extended-release corticosteroid approved to manage osteoarthritis knee pain. The benefits and risks of repeat injections have not been demonstrated.

Who should not receive ZILRETTA?

You should not receive a ZILRETTA injection if you are allergic to corticosteroids, triamcinolone acetonide, or any other component of the product.

What possible side effects of corticosteroids could occur with ZILRETTA?

Rare serious allergic reactions

Effects in the injected knee such as infection (with pain, swelling and restricted motion) or joint damage

Increased chance of getting an infection, and a decreased ability to fight an infection

Effects on hormone production. These effects can be reversible

Elevated blood pressure, sodium and water retention, and potassium loss

Intestinal perforation if you have certain gastrointestinal disorders

Weakening of bones

Changes in behavior or mood disturbances

Increased pressure inside the eye

What are the most common side effects of receiving a ZILRETTA injection?

In multiple clinical trials, the most common side effects seen in people taking ZILRETTA were joint pain, headache, joint swelling, back pain, sore throat and runny nose, upper respiratory tract infection, and bruising.

What should you tell your doctor BEFORE receiving a ZILRETTA injection?

Tell your doctor about all of the medications you are taking (including both prescription and over-the-counter medicines) and about any medical conditions, especially if you have high blood pressure, heart disease, ulcers, diverticulitis or other gastrointestinal disorders, kidney problems, diabetes, glaucoma, behavior or mood disorders, and/or infections.

What should you tell your doctor AFTER receiving a ZILRETTA injection?

Contact your doctor if you develop a fever or other signs of infection, have an increase in pain along with swelling of the injected knee, restriction of joint motion, or a general feeling of discomfort. Contact your doctor immediately if you are exposed to chicken pox or measles, or for any new or worsening changes in behavior or mood.

These are not all of the possible side effects with ZILRETTA or corticosteroid medications. Please see the full Prescribing Information at www.ZILRETTALabel.com/PI.pdf. Always contact your doctor if you have questions or experience any side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.