PREPARE FOR SUCCESS!

Make the most of your time with your doctor by preparing for your appointment.

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Taking the time to prepare for your appointment can go a long way toward getting the help you need. So take an active role, and become an advocate for yourself! Together with your doctor, you can find a solution that works for you.

I make sure to plan ahead and write down questions for my doctor. I get the most out of my visits that way.
– Kim, diagnosed with osteoarthritis of the knee in 2011

Tips to help you prepare:

Understand your insurance coverage – Talk to your doctor to see if ZILRETTA is covered for you.

If you have Medicare Part B, ZILRETTA is covered. The majority of private health insurance plans also cover ZILRETTA.

Set personal goals – Before seeing a doctor, set short- and long-term goals for managing your osteoarthritis knee pain. These can help you both decide on a treatment approach that could help you reach your goals.

Be specific – When talking about personal goals, symptoms or your experience with different treatment approaches, try to be as specific as possible.

Ask questions – Get details about the recommended treatment options, how they work, what to expect, what risks you may need to watch out for, and how long you may experience the positive effects of the treatment.

Pay attention for symptoms – Make sure to write down all of your symptoms. And think beyond pain—which activities are harder because of osteoarthritis knee pain?

Download and print out your Symptom Summary, use it, and then bring it to your appointment.

Download Your Symptom Summary

Learn about the things you can do during your appointment.

DURING YOUR APPOINTMENT

One injection. Three months of major knee pain relief is possible. Ask about the Z!

Indication and Important Risk Information

What is ZILRETTA?
ZILRETTA^® (triamcinolone acetonide extended-release injectable suspension) is an extended-release corticosteroid approved to manage osteoarthritis knee pain. The benefits and risks of repeat injections have not been demonstrated.

Who should not receive ZILRETTA?
You should not receive a ZILRETTA injection if you are allergic to corticosteroids, triamcinolone acetonide, or any other component of the product.

What possible side effects of corticosteroids could occur with ZILRETTA?

Rare serious allergic reactions
Effects in the injected knee such as infection (with pain, swelling and restricted motion) or joint damage
Increased chance of getting an infection, and a decreased ability to fight an infection
Effects on hormone production. These effects can be reversible
Elevated blood pressure, sodium and water retention, and potassium loss
Intestinal perforation if you have certain gastrointestinal disorders
Weakening of bones
Changes in behavior or mood disturbances
Increased pressure inside the eye

What are the most common side effects of receiving a ZILRETTA injection?
In multiple clinical trials, the most common side effects seen in people taking ZILRETTA were joint pain, headache, joint swelling, back pain, sore throat and runny nose, upper respiratory tract infection, and bruising.

What should you tell your doctor BEFORE receiving a ZILRETTA injection?
Tell your doctor about all of the medications you are taking (including both prescription and over-the-counter medicines) and about any medical conditions, especially if you have high blood pressure, heart disease, ulcers, diverticulitis or other gastrointestinal disorders, kidney problems, diabetes, glaucoma, behavior or mood disorders, and/or infections.

What should you tell your doctor AFTER receiving a ZILRETTA injection?
Contact your doctor if you develop a fever or other signs of infection, have an increase in pain along with swelling of the injected knee, restriction of joint motion, or a general feeling of discomfort. Contact your doctor immediately if you are exposed to chicken pox or measles, or for any new or worsening changes in behavior or mood.

These are not all of the possible side effects with ZILRETTA or corticosteroid medications. Please see the full Prescribing Information at www.ZILRETTALabel.com/PI.pdf. Always contact your doctor if you have questions or experience any side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.