ZILRETTA is the first and only FDA-approved treatment for osteoarthritis knee pain to use extended-release microsphere technology.

ZILRETTA microspheres slowly release pain medication into the knee joint for about 3 months

See how ZILRETTA microsphere technology works

News for people with Type 2 diabetes

In a small clinical trial of people with osteoarthritis of the knee and Type 2 diabetes, minimal elevation in their blood glucose levels was experienced after treatment with ZILRETTA.

Note: This clinical trial only measured blood glucose levels, not the amount of pain relief or safety in patients with Type 2 diabetes.

See how ZILRETTA worked for these five people