THE BIG NEWS IS MICROSPHERES.ZILRETTA is the first and only FDA-approved treatment for osteoarthritis knee pain to use extended-release microsphere technology. |
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What’s so special about these microspheres?
They’re tiny particles that are so small, they cannot be seen by the naked eye. They contain a medicine called triamcinolone acetonide, which helps reduce pain and inflammation caused by osteoarthritis.
Once injected directly into the knee, the microspheres stay put, slowly and continually releasing their medicine for about 3 months.
That’s big.
Staying power
ZILRETTA microspheres stay right in your knee joint—right where the pain is.
After releasing all their medicine into the knee joint, the microspheres break down and turn into carbon dioxide and water, which are naturally found in the body.
![Image of blue spheres (representative of microsphere technology) Text read: Actual microspheres are not visible to the naked eye](https://doxtm8np1ua1y.cloudfront.net/zilretta-patient/images/microsphere.png)
ZILRETTA microspheres slowly release pain medication into the knee joint for about 3 months
See how ZILRETTA microsphere technology works
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News for people with Type 2 diabetes
In a small clinical trial of people with controlled Type 2 diabetes, minimal elevation in their blood glucose level was experienced after treatment with ZILRETTA vs another corticosteroid.
Note: Corticosteroids may increase blood glucose levels. Individual patient experience may differ from what was seen in this study.
The clinical significance of this information is unknown.